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Beyond telomerase, Epitalon has secondary effects: Melatonin restoration: Epitalon restores nocturnal melatonin secretion patterns in aged animals, improving circadian regulation Antioxidant activation: Upregulation of superoxide dismutase and catalase expression Gene regulation: The Khavinson bioregulator theory proposes direct DNA binding by short peptides, though this mechanism lacks independent structural validation Epitalon targets a single primary hallmark: telomere attrition